Di Treatment. Diabetes insipidus (DI) is a disorder characterized by polydipsia polyuria and formation of inappropriately hypotonic (dilute) urine Two types exist central DI due to reduced synthesis or release of arginine vasopressin (AVP) from the hypothalamopituitary axis and nephrogenic DI due to renal insensitivity to AVP.
In infants with hereditary nephrogenic DI treatment is aimed at minimizing the polyuria and avoiding hypernatremia and volume depletion In adults therapy is usually aimed at correcting the underlying disorder or discontinuing an offending drug.
Diabetes Insipidus Treatment & Management: Approach
Fluid ReplacementDesmopressin and Other DrugsMonitoringDietary MeasuresPrecautionsMost patients with diabetes insipidus (DI) can drink enough fluid to replace their urine losses When oral intake is inadequate and hypernatremia is present replace losses with dextrose and water or an intravenous (IV) fluid that is hypoosmolar with respect to the patient’s serum Do not administer sterile water without dextrose intravenously as it can cause hemolysis To avoid hyp.
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Diabetes insipidus Symptoms, diagnosis and treatment
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